Chemical injury caused by acute alendronic acid aspiration

Glutamine Attenuates Acute Lung Injury Caused by Acid Aspiration

Inadequate ventilator settings may cause overwhelming inflammatory responses associated with ventilator-induced lung injury (VILI) in patients with acute respiratory distress syndrome (ARDS). Here, we examined potential benefits of glutamine (GLN) on a two-hit model for VILI after acid aspiration-induced lung injury in rats. Rats were intratracheally challenged with hydrochloric acid as a first...

The acute liver injury in rat caused by gold nanoparticles

Objective(s):   Gold nanoparticles (GNPs) command a great deal of attention for biomedical applications nowadays. The data about the degree of toxicity and the accumulation of gold nanoparticles in-vivo is not enough to judge.  Materials and Methods:  A total of 32 healthy male Wistar rats were randomly divided into 4 including: three GNP-treated and one control group. Groups 1, 2 and 3 receive...

N-Acetyl-Heparin Attenuates Acute Lung Injury Caused by Acid Aspiration Mainly by Antagonizing Histones in Mice

Acute lung injury (ALI) is the leading cause of death in intensive care units. Extracellular histones have recently been recognized to be pivotal inflammatory mediators. Heparin and its derivatives can bind histones through electrostatic interaction. The purpose of this study was to investigate 1) the role of extracellular histones in the pathogenesis of ALI caused by acid aspiration and 2) whe...

the acute liver injury in rat caused by gold nanoparticles

objective(s):   gold nanoparticles (gnps) command a great deal of attention for biomedical applications nowadays. the data about the degree of toxicity and the accumulation of gold nanoparticles in-vivo is not enough to judge.  materials and methods:  a total of 32 healthy male wistar rats were randomly divided into 4 including: three gnp-treated and one control group. groups 1, 2 and 3 receive...

Alendronic acid for antipsychotic-related osteopenia.